Medical Insider – Dr. Cora E. Lim

Inflammatory Myopathies

What are Inflammatory myopathies? These are muscle diseases caused by inflammation. They are autoimmune diseases where the body’s immune system attacks its own muscles by mistake. 

The most common inflammatory myopathies are dermatomyositis and polymyositis; however, this is a rapidly evolving field and new inflammatory myopathies are being described. 

Inflammatory myopathies cause muscle weakness, usually in the neck, shoulders, and hips. 

Dermatomyositis causes skin rashes also. Muscle weakness is a common symptom. Some people can have breathing problems. 

People of all ages and races may get inflammatory myopathies, but they’re rare. 

Children usually get them between ages 5 and 10. Adults usually get these diseases between 40 and 50. Women get inflammatory myopathies twice as often as men. 

What Are the Signs/Symptoms? 

The most common sign of inflammatory myopathies is weakness in the large muscles of the shoulders, neck, or hips. Inflammation damages tissue so you lose strength in these muscles. Inflammatory myopathies may cause problems like these: Trouble climbing stairs, lifting objects over your head, or getting out of a seat Choking while eating or intake of food into the lungs 

Shortness of breath and cough 

Dermatomyositis causes skin rashes that look like red or purple spots on the eyelids, or scaly, red bumps on the elbows, knuckles, or knees 

Children may also develop calcinosis, white spots on their skin from calcium deposits, or vasculitis, a blood vessels inflammation that leads to skin lesion. 

What Are Common Treatments? 

Diagnosing inflammatory myopathies starts with a muscle strength exam. A rheumatologist may also do blood tests to measure muscle enzymes and myositis specific antibodies, electromyogram (EMG) to measure electrical activity in the muscles, or magnetic resonance imaging (MRI) to look for muscle damage. You may need a muscle biopsy. 

These diseases may be linked to cancer, so tests to rule out cancer may be needed. 

Living with Inflammatory Myopathies 

Good health habits are important for long-term management of inflammatory myopathies. Eat a healthy, well-balanced diet, get regular exercise, and stay at a healthy weight. 

People with dermatomyositis should use sun protection so rashes don’t worsen. Limit your time outdoors and use sunscreen when you go outside. 

If you have trouble swallowing, eat soft foods or puree solid foods in a blender. To prevent choking if you are bedbound, sit up in bed to eat. 

People with myopathy may look healthy and normal. It is important for employers, teachers, and family members to understand the limits that muscle weakness causes in people with myopathy.