ActiGraft offers several key advantages over conventional dressings, primarily driven by its unique biological mechanism and supported by clinical evidence demonstrating superior healing outcomes.
Superior Clinical Efficacy
Clinical studies show ActiGraft is significantly more effective at closing chronic, hard-to-heal wounds than standard treatments:
· Faster and More Likely to Heal: A 2026 real-world study found ActiGraft led to significantly faster healing than advanced dressings for chronic leg ulcers. In diabetic foot ulcers (DFUs), a randomized trial reported 51% complete closure at 12 weeks with ActiGraft vs. 18% with standard care.
· Higher Healing Odds: The same DFU trial found ActiGraft conferred 2.7 times higher odds of healing.
· High Closure Rates: In one study, ActiGraft achieved a 68.8% closure rate, compared to 40.3% for advanced dressings.
· Rapid Wound Area Reduction: Case series data show a mean wound area reduction of 83% at 5 weeks.
Biologically Active, Not Just a Covering
Unlike passive conventional dressings, ActiGraft is an autologous (patient-derived) therapy that actively restarts the body’s healing process. It is made from a small sample of the patient’s own blood, processed at the bedside in about 5-10 minutes. The resulting blood clot acts as a biological scaffold delivering growth factors directly to the wound to rebalance the healing environment.
Practical Benefits for Patients and Clinicians
· Reduced Pain: Requires minimal wound handling, making treatment more comfortable.
· Cost-Effective: Can cover the wound for long periods with minimal care between applications.
· Simple Logistics: Requires no capital equipment and can be prepared at the point of care.
· Safe and Hypoallergenic: Being made from the patient’s own blood eliminates the risk of disease transmission or allergic reactions associated with products from animal or human donors.
· Versatile: Suitable for various wound types, including those with exposed bone or tendon, and on large or irregularly shaped wounds up to 56 cm².
Additional Advantages
· Culturally Sensitive: Contains no bovine, porcine, or placental products, making it suitable for patients with religious or cultural restrictions.
· Proven Safety: In over 10,000 patient applications, no wound infections were reported.
In summary, ActiGraft is not just a dressing but a biologically active, patient-derived therapy that actively restarts healing, offering a more effective and efficient solution for chronic wounds compared to conventional standards of care.
P.S.
ActiGraft is now available in Bohol only/exclusively at our Advanced Wound Care Center
ZP
Zandro Paolo Plateros
plateros@gmail.com